From the start, Biology: How Life Works was envisioned not as a reference book for all of biology, but as a resource focused on foundational concepts, terms, and experiments. In preparing the second edition, we carefully considered the latest breakthroughs and incremental, but nevertheless significant, changes across the fields of biology. We also reached out to both adopters, instructors not using our book, and primary literature to determine what concepts and details would be relevant, important, and necessary additions. Hear author Dan Hartl explain the process of revising the text, media, and assessment for the second edition.