Second Edition   ©2015

Molecular Biology

Principles and Practice

Michael M. Cox (University of Wisconsin-Madison) , Jennifer Doudna (University of California, Berkeley) , Michael O'Donnell (Rockefeller University)

  • ISBN-10: 1-4641-2614-3; ISBN-13: 978-1-4641-2614-7; Format: Cloth Text, 944 pages

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Moment of Discovery
Each chapter opens with a description of a significant breakthrough in molecular biology relevant to that chapter, as told by the scientist who made the discovery

Key Conventions
These brief paragraphs clearly lay out for students some fundamental principles often glossed over by instructors and textbooks.

How We Know
This end-of-chapter section combines fascinating stories of research and researchers with actual experimental data for students to analyze, often drawing on the work of the scientist featured in the chapter’s "Moment of Discovery."

Problems (including Data Analysis Problem)
Problem sets at the end of each chapter give students the opportunity to think about and work with the chapter’s key ideas. Each problem set\ concludes with a Data Analysis Problem, giving students the crucial experience of interpreting real data from actual research (most often the work described in the "How We Know" section). Solutions to the problems can be found on the companion Web site.

Unanswered Questions
A short section at the end of each chapter describes important areas still open to discovery, showing students that even well-covered subjects such as nucleic acid structure and DNA replication are far from fully explored.

Throughout each chapter, special features focus on fascinating topics that enhance student understanding of the concepts:

  • Medicine looks at diseases that arise from defects in biochemical pathways, or examples of how concepts learned in molecular biology have contributed drug therapies or other treatments.
  • Technology focuses on cutting-edge molecular biology methods that students will likely be hearing about or even using in the future.
  • Evolution reveals the role of molecular biology research in understanding key biological processes and the connections between organisms.
  • A Closer Look highlights a wide variety of additional, intriguing topics.