Molecular Cell Biology
Eighth Edition   ©2016

Molecular Cell Biology

Harvey Lodish (Massachusetts Institute of Technology) , Arnold Berk (University of California, Los Angeles) , Chris A. Kaiser (Massachusetts Institute of Technology) , Monty Krieger (Massachusetts Institute of Technology) , Anthony Bretscher (Cornell University) , Hidde Ploegh (Massachusetts Institute of Technology) , Angelika Amon (Massachusetts Institute of Technology) , Kelsey C. Martin (University of California, Los Angeles)

  • ISBN-10: 1-4641-8339-2; ISBN-13: 978-1-4641-8339-3; Format: Cloth Text

New Co-Author, Kelsey Martin, UCLA
Dr. Martin teaches basic neurobiology to undergraduate, graduate, dental, and medical students. Her laboratory uses Aplysia and mouse models to understand the cell and molecular biology of long-term memory formation. Her group has made important contributions to elucidating the molecular and cell biological mechanisms by which experience changes connections between neurons in the brain to store long-term memories—a process known as synaptic plasticity.

Revised, Cutting Edge Content:

Chapter 1, Molecules, Cells, and Model Organisms, a complete overview of evolution, molecules, different forms of life, and model organisms used to study cell biology, now includes a survey of eukaryotic organelles (previously in Chapter 9).

Chapter 4, Culturing and Visualizing Cells (previously Chapter 9) has been moved forward to reflect the increasing importance of techniques used to study cells. Updates include coverage of light sheet microscopy, super-resolution microscopy, and two-photon excitation microscopy.

Chapter 12, Cellular Energetics, now brings together all aspects of mitochondria and chloroplast structure and function, including a new discussion of mitochondrial-associated membranes (MAMs) and of communication between mitochondria and the rest of the cell.

More Accessible Coverage of Cell Signaling
Chapter 15, Signal Transduction and G Protein-Coupled Receptors
begins with an overview of the concepts in cell signaling and methods for studying cell signaling, then follows with examples of G protein-coupled receptors performing multiple roles in different cells.

Chapter 16, Signaling Pathways That Control Gene Expression now focuses on gene expression, beginning with a new discussion of Smads. Further examples cover the major signaling pathways that students will encounter in cellular metabolism, protein degradation, and cellular differentiation. Of particular interest is a new section on Wnt and Notch signaling pathways controlling stem cell differentiation in planaria. The chapter ends by describing how signaling pathways are integrated to form a cellular response in insulin and glucagon control of glucose metabolism.

Chapter 22, New Cells of the Nervous System, thoroughly revised by new coauthor Kelsey Martin, highlights several new developments in the field, including
• Optogenetics, a technique that uses channel rhodopsins and light to perturb the membrane                potential of a cell
• Signals that govern the formation and pruning of neural pathways
• Signals and molecular mechanisms underlying synaptic plasticity (in an entirely new section on learning and memory)

New and Enhanced Molecular Models
From the precise fit required for tRNA charging, to the conservation of ribosome structure, to the dynamic strength of tropomyosin and troponin in muscle contraction, these figures communicate the complex details of molecular structure that cannot be conveyed in schematic diagrams alone.
Built around the biggest classroom issues you face, LaunchPad gives students everything they need to prepare for class and exams, while giving instructors everything they need to quickly set up a course, shape the content to their syllabus, craft presentations and lectures, assign and assess homework, and guide the progress of individual students and the class as a whole.

In the Lodish Molecular Cell Biology 8e LaunchPad:

An interactive e-book integrates the text and all student media, including:
• NEW! Interactive Case Studies, guiding students through applied problems related to important concepts; topics include cancer, diabetes and cystic fibrosis.
• Over 60 Animations, revised and modified to match key figures from the text, illustrating difficult or important structures and processes.
 LearningCurve adaptive quizzing, which provides individualized question sets and feedback based on each student’s responses. All the questions are tied back to the e-book to encourage students to read the book in preparation for classtime and exams.
• Concept Check quizzes testing student understanding of the most important concepts of each section.
• A newly digitized Solutions Manual with answers to questions in the end of chapter, as well as answers to several of the study tools on LaunchPad, including Review the Concepts and Analyze the Data features.
• Videos showing real cell processes as they appear in the lab.
• Analyze the Data questions asking students to apply critical thinking and data analysis skills to solving complex problems.
• Classic Experiments primers on historical experiments important to cellular and molecular biology.

The Video Assignment Tool makes it easy to assign and assess video-based activities and projects, as well as providing a convenient way for students to submit video coursework.

LaunchPad Gradebook gives a clear window on performance for the whole class, for individual students, and for individual assignments.

A streamlined interface helps students manage their schedule of assignments, while social commenting tools let them connect with classmates, and learn from each other. 24/7 help is a click away, accessible from a link in the upper right hand corner.

Optional pre-built chapter units, curated by the authors, can be used as is or customized. Or choose not to use them and build your course from scratch.

Book-specific instructor resources including:
• All Figures and Photos from the text are optimized for classroom presentation and provided in several formats and with and without labels.
• A comprehensive Test Bank provides a variety of questions for creating quizzes and exams.
• Lecture Slides built around high-quality versions of text figure provide a starting point for in-class presentations.
• Clicker Questions in slide format help instructors promote active learning in the classroom.

Easy LMS integration into your school’s learning management system.