Introduction to Genetic Analysis by Anthony J.F. Griffiths; Susan Wessler; Sean Carroll; John Doebley - Eleventh Edition, 2015 from Macmillan Student Store

Introduction to Genetic Analysis

Eleventh Edition ©2015 Anthony J.F. Griffiths; Susan Wessler; Sean Carroll; John Doebley

With each edition, An Introduction to Genetic Analysis (IGA) evolves discovery by discovery with the world of genetic research, taking students from the foundations of Mendelian genetics to the latest findings and applications by focusing on the landmark experiments that define the field.
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Introduction to Genetic Analysis by Anthony J.F. Griffiths; Susan Wessler; Sean Carroll; John Doebley - Eleventh Edition, 2015 from Macmillan Student Store

With each edition, An Introduction to Genetic Analysis (IGA) evolves discovery by discovery with the world of genetic research, taking students from the foundations of Mendelian genetics to the latest findings and applications by focusing on the landmark experiments that define the field.

With its author team of prominent scientists who are also highly accomplished educators, IGA again combines exceptional currency, expansive updating of its acclaimed problem sets, and a variety of new ways to learn genetics. Foremost is this edition's dedicated version of W.H. Freeman's breakthrough online course space, LaunchPad, which offers a number of new and enhanced interactive tools that advance IGA's core mission: to show students how to analyze experimental data and draw their own conclusions based on scientific thinking while teaching students how to think like geneticists.

Features

New to This Edition

LAUNCHPAD

Developed with extensive feedback from instructors and students, LaunchPad offers:

Pre-built Units for each chapter, curated by experienced educators, with media for each chapter organized and ready to assign or customize to suit your course.

All online resources for the text in one location, including:
LearningCurve adaptive quizzing (see below)—now with more questions at all levels

    New Problem-solving videos—step-by-step, whiteboard-style demonstrations of problems students often find difficult.

      Animations of genetic processes and experiments (six new)—every animation now includes assessment questions. Icons in the text showing students when to review them.

        Updated Unpacking the Problem problem-solving tutorials, on topics students struggle with, including:

          • Chi-square Analysis (Chs. 4/5)
          • Pedigree Analysis (Ch. 6)
          • Epistasis (Ch. 6)
          • Molecular Biology Techniques (Ch. 10)
          • Mutations on Gene Expression (Ch. 12)
          • Development (Ch. 13)
          • Population Genetics (Ch. 18)
          • Quantitative Genetics (Ch. 19)

              Online versions of the new edition’s expanded end-of-chapter problem sets, plus and larger test bank

              Intuitive and useful analytics, with a Gradebook that reveals how the class is doing individually and as a whole.

              A streamlined and intuitive interface that lets instructors build an entire course in minutes.


              LearningCurve

              In a game-like format, LearningCurve adaptive and formative quizzing provides an effective way to get students involved in the coursework. With an expanded base of questions at all level for this edition, LearningCurve offers:

              • A unique learning path for each student, with quizzes shaped by each individual’s correct and incorrect answers.

              • A Personalized Study Plan, to guide students’ preparation for class and for exams.

              • Feedback for each question with live links to relevant e-book pages, guiding students to the reading they need to do to improve their areas of weakness.


              NEW CONTENT

              New Chapter 1
              The new edition begins with four current stories of how genetics is currently being applied to research into human disease, mutation rates and reproduction, evolution, and agriculture. These stories introduce basic concepts while connecting the course to immediate, real-world issues piquing student interest in genetics. The chapter still offers a short history of the field, but without an explicit overview of genetics topics.

              Thoroughly Revised Chapter 14, Genomes and Genomics
              New introduction               features real-life application of medical genomics.

              New coverage of:

              • Illumina sequencing
              • RNA-seq
              • Non-coding functional elements in the genome, including the ENCODE project

                Expanded coverage of comparative genomics:

                • Section 14.5 Comparative Genomics of Humans with Other Species includes a new example: the vitellogenin gene
                • Section 14.6 Comparative Genomics and Human Medicine includes a new section on exome sequencing and its role in human medicine


                  Additional New Coverage Highlights

                  • A new introduction to forward genetics and the role of genetic analysis in identifying traits of single-gene inheritance (Ch 2)
                  • Concepts of dominance and recessiveness now explained in terms of haplosufficiency and haploinsufficiency (Ch 2)
                  • Revised section on chi-square analysis (Ch. 4)
                  • New coverage of horizontal and vertical transmission (Ch. 5)
                  • Updated coverage of dynamic chromatin, including chromatin remodeling, histone modification, and histone variants (Ch. 12)
                  • Genomic surveillance of transposable elements (pi-clusters and CRISPR loci) added. (Ch. 15)
                  • Nucleotide excision repair (NER) pathway updated to reflect current knowledge (Ch. 16)
                  • New coverage of MacDonald and Kreitman method for detecting positive selection (Ch. 20)

                  　New Learning Objectives
                  Each chapter begins with a list of specific learning outcomes, giving students a clear roadmap/study plan for navigating the material, reviewing and reinforcing key ideas, and preparing for exams. Chapter coverage and the end-of-chapter questions give instructors plenty of opportunities for outcomes-based assessments.
                  Expanded Assessment
                • More End-of-Chapter problems at all levels, in the book and online in LaunchPad
                • More text bank and LearningCurve adaptive quizzing questions in LaunchPad
                • Animations now include assessment questions
"Griffiths is a superb text with well-qualified authors, earnest academic rigor (appropriate for college students), and content that is well supported by end of chapter problems. I like that the authors have a clear focus in each chapter and use examples to support their pedagogical goals - the "cool" examples are used conservatively in direct support of the goals for each chapter."
--Jay Brewster, Pepperdine University

"Thorough, well-written, it has always been a solid text."
--Matthew White, Ohio University 

"I always feel that teaching genetics is exciting because nearly every chapter has a Nobel-winning experiment. The writing style of this chapter [13] certainly captures that excitement."
--Henry Chang, Purdue University
"Griffiths is a classic text that does a good job overall. For the most part it is very clear in its explanations. The organization is fairly traditional, with classic Mendelian genetics presented first."
--Jennifer Powell, Gettysburg College

Digital Options

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Launchpad

Get the e-book, do assignments, take quizzes, prepare for exams and more, to help you achieve success in class.

Schedule Launchpad Demo

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E-book

Read online (or offline) with all the highlighting and notetaking tools you need to be successful in this course.

Table of Contents

1. The Genetic Approach to Biology
2. Single-Gene Inheritance
3. Independent Assortment of Genes
4. Mapping Eukaryote Chromosomes by Recombination
5. The Genetics of Bacteria and Their Viruses
6. Gene Interaction
7. DNA: Structure and Replication
8. RNA: Transcription and Processing
9. Proteins and Their Synthesis
10. Gene Isolation and Manipulation
11. Regulation of Gene Expression in Bacteria and Their Viruses
12. Regulation of Gene Expression in Eukaryotes
13. The Genetic Control of Development
14. Genomes and Genomics
15. The Dynamic Genome
16. Mutation and Repair
17. Large-Scale Chromosomal Changes
18. Population Genetics
19. The Inheritance of Complex Traits
20. Evolution of Genes and Traits

Anthony J.F. Griffiths

Anthony Griffiths is a Professor of Botany, Emeritus, at the University of British Columbia. His research focuses on the developmental genetics of fungi, using the model fungus Neurospora crassa. He has served as President of the Genetics Society of Canada and Secretary-General of the International Genetics Federation.

Susan R. Wessler

Susan R. Wessler is Distinguished Professor of Genetics in the Department of Botany and Plant Sciences at the University of California, Riverside. Her research focuses on plant transposable elements and their contribution to gene and genome evolution. Wessler was elected to the National Academy of Sciences in 1998. As a Howard Hughes Medical Institute Professor, she developed and teaches a series of Dynamic Genome Courses where undergraduates can experience the excitement of scientific discovery.

Sean B. Carroll

Sean B. Carroll is an Investigator at the Howard Hughes Medical Institute and Professor of Molecular Biology and Genetics at the University of Wisconsin, Madison. Carroll is a leader in the field of evolutionary developmental biology and was elected to the National Academy of Sciences in 2007. He is also the author of Endless Forms Most Beautiful, The Making of the Fittest, and Remarkable Creatures (a finalist for the National Book Award, non-fiction, 2009).

John Doebley

John Doebley is a Professor of Genetics at the University of Wisconsin-Madison. He studies the genetics of crop domestication, using the methods of population and quantitative genetics. He was elected to the National Academy of Sciences in 2003 and served as the President of the American Genetic Association in 2005. He teaches General Genetics at the University of Wisconsin.

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