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Julien's Primer of Drug Action
Fourteenth Edition| ©2019 Claire D. Advokat; Joseph E. Comaty; Robert M. Julien
Julien’s Primer of Drug Action continues to evolve side by side with the field it covers providing a thoroughly up to date look at psychotherapeutic and recreational drugs, including the latest research and the newest formulations.
The thoroughly updated 14th edition featur...
Julien’s Primer of Drug Action continues to evolve side by side with the field it covers providing a thoroughly up to date look at psychotherapeutic and recreational drugs, including the latest research and the newest formulations.
The thoroughly updated 14th edition features:
- New coverage of opioids of abuse, and drugs used to treat of opioid dependence and opioid overdose.
- New research on the use of marijuana to treat Alzheimers, PTSD, and Epilepsy.
- New coverage of pharmacological, physiological, and psychoactive effects of synthetic marijuana including its toxicity.
- New research on Cannabidiol (CBD) and its therapeutic uses
- New research of the efficacy of antipsychotics to treat dementia, Parkinson’s, bipolar, OCD, PTSD,
- New research on hallucinogenics for the treatment of various disorders including MDMA for the treatment of PTSD, Psilocybin for treatment of depression and end-of-life anxiety, and Ayahuasca to treat psychiatric disorders
- The use of genetic testing to predict effectiveness of antidepressant treatment
- New research on the use of ketamine for the treatment of depression
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The most current and comprehensive guide to psychopharmacology available.
Julien’s Primer of Drug Action continues to evolve side by side with the field it covers providing a thoroughly up to date look at psychotherapeutic and recreational drugs, including the latest research and the newest formulations.
The thoroughly updated 14th edition features:
- New coverage of opioids of abuse, and drugs used to treat of opioid dependence and opioid overdose.
- New research on the use of marijuana to treat Alzheimers, PTSD, and Epilepsy.
- New coverage of pharmacological, physiological, and psychoactive effects of synthetic marijuana including its toxicity.
- New research on Cannabidiol (CBD) and its therapeutic uses
- New research of the efficacy of antipsychotics to treat dementia, Parkinson’s, bipolar, OCD, PTSD,
- New research on hallucinogenics for the treatment of various disorders including MDMA for the treatment of PTSD, Psilocybin for treatment of depression and end-of-life anxiety, and Ayahuasca to treat psychiatric disorders
- The use of genetic testing to predict effectiveness of antidepressant treatment
- New research on the use of ketamine for the treatment of depression
Features
- “Did you know” boxes highlight high interest topics relevant to the chapter material Did you boxes new to the 14th edition include: Optogenetics; Hangover free Alcohol; the Microbiome and your mood, Powdered Caffeine Fatalities.
- Study Questions at the end of each chapter.
- Part 1 introduces students to the basic concepts of pharmacokinetics: how the body acts on drugs; Pharmacodynamics: how drugs act on the body; and Neuroscience. Each subsequent chapter applies those concepts and explores the pharmacokinetics and pharmacodynamics of each drug examined.
New to This Edition
- Chapter 9, Cannabis, features: new material on the legal status of marijuana, new coverage of marijuana usage, new research on Cannabidiol and it’s pharmokinetics; new research on the use of marijuana to treat Alzheimers, PTSD, and Epilepsy. New coverage of pharmacological, physiological, and psychoactive effects of synthetic marijuana including its toxicity.
- Chapter 10, Opioids features: New section Opioid Misuse and Abuse presents the scope of the current opioid epidemic in the US; New discussions of the recent increase in heroin use; new formulations of hydrocordone and oximorphone, and new research into methadone use and effects, New section on the Use of Buprenorphine for the Treatment of Opioid Dependence. New research on and new formulations of drugs used to treat opioid overdose: Naltrexone, Nalmefene, and Naloxone. New discussion of Illicit Opioids of Abuse include coverage of Synthetic Fentanyl Derivatives and New research on the use of Kratom, an herbal drug with opiate effects.
- Chapter 5 Ethyl Alcohol and the Inhalants of Abuse includes new research on the effect of persistent alcohol use in adolescence; pharmacotherapies that maintain abstinence from alcohol and prevent relapse including opioid antagonists and ketamine; and a new appendix on alcohol use disorder.
- Chapter 11, Antipsychotic Drugs s has been completely revised to include new research on the causes of schizophrenia, new research of the efficacy of antipsychotics to treat dementia, parkinsons, bipolar, OCD, PTSD, new research on the efficacy and toxicity of first generation antipsychotics v. Second generation anti psychotic, and discussion new antipsychotics in the pipeline.
- Chapter 6 Caffeine and Nicotine includes New research on how nicotine effects the brain, a new section smoking and mental health; new research on effectiveness of Chantix and Buboprion for nicotine dependence, a new material on the effects of e-cigarettes and vapor products, their use in smoking cessation, and their use among young people,
- Chapter 7, Cocaine, the Amphetamines, and Other Psychostimulants, includes new research on the effects of bath salts, new data on their usage, and discussion of new bath salt formulations.
- Chapter 8, Psychadelic Drugs includes new research on MDMA for treatment of PTSD, Psychsiblin for treatment of depression and end-of-life anxiety, and ayahuasca to treat psychiatric disorders
- Chapter 12 Antidepressant drugs includes, new research on the use of ketamine for the treatment of depression; New research on effectiveness of antidepressants; The use of genetic testing to predict effectiveness of antidepressant treatment; revised discussion of treatment resistant depression and drugs used to augment antidepressants.
- Chapter 14, Drugs Used to Treatment Bipolar disorders features new research on the efficacy and mechanism of action of treatment for bipolar disorder as well the pathophysiology of bipolar disorder.
- Chapter 15, Child and Adolescent Psychopharmacology features New research on the effects of cannabis, alcohol, nicotine, stimulants, and antidepressant use during pregnancy. New material regarding the use of illicit drugs during teenage years, including the effects of persistent marijuana, alcohol, and stimulant use in the teen years. New research on the treatment of psychiatric disorders in adolescence.
- Chapter 16 Geriatric Psychopharmacology includes material on the treatment of Dementia, Alzheimers, and Parkinsons disease as well as use of antipsychotics in elderly patients.
- Chapter 17 Challenging Times for Mental Illness includes, updated discussion on the epidemiology of mental illness. New discussion of updated ways of studying mental illness. New discussion of the resurgence of non-pharmaceutical treatment of mental illness.
“The book stands out by providing the more detailed information of any similar psychopharmolocolgy text...[it] is well written and the literature review is strong”
— Joshua Berk, College of William and Mary
“Clear writing that is neither too sophisticated nor too simple”
— Lawrence Wichlinski, Carleton College“The level of detail of this text is perfect for my students, most of who are new to pharmacology. I like the organization. It introduces important concepts first and then applies them to the most common recreational and psychotherapeutic drugs”
— Marc Dignman, Penn State University


Julien's Primer of Drug Action
Fourteenth Edition| ©2019
Claire D. Advokat; Joseph E. Comaty; Robert M. Julien
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Julien's Primer of Drug Action
Fourteenth Edition| 2019
Claire D. Advokat; Joseph E. Comaty; Robert M. Julien
Table of Contents
Part 1 Introduction to Psychopharmacology: Biological Basis of Drug Action
Chapter 1 Pharmacokinetics: How Drugs Are Handled by the Body
Chapter 2 The Neuron, Synaptic Transmission, and Neurotransmitters
Chapter 3 Pharmacodynamics: How Drugs Act
Part 2 Pharmacology of Drugs of Abuse 93
Chapter 4 Epidemiology and Neurobiology of Addiction
Chapter 5 Ethyl Alcohol and the Inhalants of Abuse
Chapter 7 Cocaine, the Amphetamines, and Other Psychostimulants
Chapter 8 Psychedelic Drugs
Chapter 9 Cannabis: A New Look at An Ancient Plant
Chapter 10 Opioid Analgesics
Part 3 Psychotherapeutic Drugs
Chapter 11 Antipsychotic Drugs
Chapter 12 Antidepressant Drugs
Chapter 13 Anxiolytics, Sedative Hypnotics, Anesthetics, and Anticonvulsants
Chapter 14 Drugs Used to Treat Bipolar Disorder
Part 4 Special Populations and Integration
Chapter 15 Child and Adolescent Psychopharmacology
Chapter 16 Geriatric Psychopharmacology
Chapter 17 Challenging Times for Mental Health
Appendix A: Quick Reference to Psychotropic Medications
Appendix B: Introduction to Epigenetics


Julien's Primer of Drug Action
Fourteenth Edition| 2019
Claire D. Advokat; Joseph E. Comaty; Robert M. Julien
Authors

Claire D. Advokat
Claire Advokat received her Ph.D. in physiological psychology from Rutgers University, following which she completed an NIH Postdoctoral Fellowship at the College of Physicians and Surgeons of Columbia University in New York City. She then served on the faculty of the Department of Pharmacology at the University of Illinois Health Sciences Center in Chicago. In 1989 she joined the Department of Psychology at Louisiana State University, where she served as the Faculty Senate President (2004–2005), retiring in 2012 as an emerita professor. Her research area is psychopharmacology, specifically drugs used in the treatment of psychiatric and behavioral disorders. She has published over 80 articles, and received funding for her studies from the National Institute of Drug Abuse (NIDA), the Spencer Foundation, the Board of Regents of Louisiana, the State of Louisiana, and the pharmaceutical firm NPS. She received a university teaching award in 2005, served as an ad hoc reviewer for 20 journals, and serves on the editorial board of The Journal of Attention Disorders.

Joseph E. Comaty
Joseph E. Comaty received his M.S. in experimental psychology from Villanova University; his Ph.D. in psychology with a specialization in clinical neuropsychology from the Rosalind Franklin University of Medicine and Science, in Illinois; and his postdoctoral Masters Degree in clinical psychopharmacology from Alliant University/CSPP in California. He is a licensed psychologist under the Louisiana State Board of Examiners of Psychologists (LSBEP) and a licensed medical psychologist under the Louisiana State Board of Medical Examiners. He retired from the Louisiana Department of Health and Hospitals, Office of Behavioral Health in 2013 where he was the Chief Psychologist and Medical Psychologist and Director of the Division of Quality Management. He is an adjunct assistant professor in
psychology at Louisiana State University (LSU) in Baton Rouge and serves as emeritus faculty of the Southern Louisiana Internship Consortium (SLIC) in psychology at LSU. He has served as a member and chair of the LSBEP; he is a member and current chair of the RxP Designation Committee of APA, and a site reviewer for APA’s Committee on Accreditation. He is a member of the Model Act and Regulation Revision Committee for the Association of State and Provincial Psychology Boards (ASPPB). His research is in the areas of behavior therapy, pharmacology, and clinical psychopharmacology. He is the author of over 50 articles, book chapters, and presentations. He has served on federal grant review committees
and has been a reviewer for Psychiatric Services; The Journal of Gerontology: Psychological Sciences; and the Journal of Behavioral Health Services and Research.

Robert M. Julien, Ph.D.
Robert M. Julien, M.D., received his M.S. and Ph.D. in pharmacology from the
University of Washington and his medical degree from the University of California at Irvine. His many research articles focus on the psychopharmacology of sedative and antiepileptic drugs. Formerly an associate professor of pharmacology and anesthesiology at the Oregon Health Sciences University, Dr. Julien has retired from the practice of anesthesiology and is currently a psychopharmacology consultant in Portland, Oregon.
University of Washington and his medical degree from the University of California at Irvine. His many research articles focus on the psychopharmacology of sedative and antiepileptic drugs. Formerly an associate professor of pharmacology and anesthesiology at the Oregon Health Sciences University, Dr. Julien has retired from the practice of anesthesiology and is currently a psychopharmacology consultant in Portland, Oregon.


Julien's Primer of Drug Action
Fourteenth Edition| 2019
Claire D. Advokat; Joseph E. Comaty; Robert M. Julien
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Claire D. Advokat; Joseph E. Comaty; Robert M. Julien | Fourteenth Edition | ©2019 | ISBN:9781319138073
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Julien's Primer of Drug Action
Fourteenth Edition| 2019
Claire D. Advokat; Joseph E. Comaty; Robert M. Julien
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