Lehninger Biochemistry: Core Concepts and Applications
Michael M. Cox et al.
First Edition | ©2025
Biochemistry
The Power of Life Itself
Biochemistry isn’t about memorizing pathways—it's about understanding how life shapes the world. From cellular energy to groundbreaking medicines, its impact is everywhere. Inspire students to not only study biochemistry, but also to see its connection to everyday life.
Try the AI TutorBiochemistry Products by Course
One-Semester Introductory Biochemistry
Two-Semester Introductory Biochemistry
Classroom Solutions for Biochemistry
Achieve Courseware
Lab Solutions
Custom Content
Instructor Resources
Achieve Courseware
Achieve for Biochemistry helps students understand molecular structures and biochemical pathways by connecting mechanisms to function through guided practice, interactive models, and AI-powered support.
Assessments
Assess student understanding of biochemical mechanisms and pathways with tools designed to surface misconceptions and reinforce connections across topics. Key assessments include:
- Pre-built chapter homework includes hints, targeted feedback and a new AI Student Tutor for every problem. Using a Socratic approach, the AI Tutor assesses and guides student understanding as they work through biochemistry homework, surfacing misconceptions and gaps in reasoning in real time."
- Adaptive Quizzing checks understanding of core biochemistry concepts through personalized questions and targeted feedback, helping students identify gaps and revisit key ideas in context.
- iClicker enables real-time concept checks during class to uncover misconceptions around structure–function relationships, reaction mechanisms, and pathway logic.
- Respondus® LockDown Browser Integration provides a secure and trustworthy exam environment for your biochemistry assessments.
Personalized Learning Support
Empower your students to master challenging biochemistry concepts with personalized learning tools.
- The AI Student Tutor provides step-by-step, adaptive guidance that helps students build confidence as they work through challenging biochemistry concepts at their own pace without giving away answers.
- Detailed assignment feedback offers actionable explanations that help students learn from mistakes and strengthen their understanding of biochemical concepts over time.
- Goal-setting and Reflection Surveys help students set learning goals, reflect on progress, and build metacognitive skills, while giving instructors insight into learning trends.
Dynamic, Engaging Content
Help students make sense of complex biochemical systems with interactive tools designed to support pathway reasoning and conceptual understanding.
Interactive Metabolic Maps
Help students navigate biochemical pathways by zooming between a big-picture view and detailed reaction steps. Guided tours and integrated questions support pathway reasoning and help students see how individual processes connect within larger systems.
Interactive Figures & Media
Bring biochemical processes to life with interactive figures that allow students to explore molecular functions and system dynamics. Paired assessments encourage active engagement and help students move beyond surface understanding.
Instructor Tools & Course Management
Save time preparing your biochemistry course with ready-to-use teaching materials and integrated tools that simplify setup and grading.
- Ready-to-use instructor resources, such as presentation slide decks with embedded active learning opportunities, question banks, classroom activities, and more, make it easier to prepare and teach your biochemistry course. Explore what is available with a free Achieve sample course!
- LMS integration simplifies course setup, assignments, and grading.
- Real-time analytics allow you to easily monitor student progress and identify areas needing attention early on.
- Gradebook tools to monitor student and classroom performance, and easily see trends.
What’s New in Achieve (Spring 2026)
Achieve is continually improving to meet the needs of today’s classrooms. Here’s a look at what’s coming in Spring 2026:
- Peer Connector helps students get to know each other by responding to short prompts and discovering shared interests or commonalities with peers. These small moments of connection foster community, build inclusive, supportive learning environments, and are correlated with improved learner performance.
- Short-form Writing adds AI-powered tools that help instructors create stronger prompts and rubrics (Short Form Writing Creator, Beta) and streamline grading through rubric-aligned evaluations and transparent, reviewable feedback (Short Form Writing Analyzer, Beta).
Explore the full lineup of updates and improvements here.
Lab Solutions
Biochemistry is best learned through experimentation and discovery. Whether in-person or virtual, these lab solutions make hands-on learning accessible, engaging, and effective.
Ready-to-Use Labs
Streamline your course creation with expertly designed, pre-built lab resources. Access a rich library of interactive content, comprehensive lab manuals, and tailored assessments, all crafted to save you time while delivering exceptional learning experiences.
Chemistry Lab Notebooks
Durable, carbonless lab notebooks make it easy for students to record, organize, and retain their lab notes while providing instructors with accessible copies for grading and review. Chemistry lab notebooks are available with 50 or 100 carbonless page sets.
Customizable Lab Content
Design interactive and engaging lab experiences tailored to your course needs. Choose from ready-to-use resources, combine them, or create your own materials, including manuals, experiments, animations, and assessments. Provide your students with labs that fit your objectives and enhance their learning experience.
Interactive Lab Simulations
Enhance hands-on learning with virtual lab experiments and simulations, offering a safe, risk-free environment for practice. Dive deeper with 3D molecular models and animations that improve spatial understanding through engaging, interactive visuals.
Custom Content
Customize your biochemistry materials to align with your teaching style, course objectives, and student needs.
Create Your Own Materials
Easily create course content that fits your teaching style and goals. From editable ebooks to custom lab exercises and assessments, you have the flexibility to design materials that meet your unique needs.
Customize Prebuilt Course Resources
Don’t have time to create course materials from scratch? Combine prebuilt resources—like images, videos, and interactive elements—or seamlessly integrate your own materials to create highly personalized resources. Keep lessons fresh and engaging, with the flexibility to update or replace content anytime.
Support Every Step of the Way
Not sure where to start? Macmillan Learning experts work with you to create and customize everything your Biochemistry course needs—textbooks, manuals, labs, interactive simulations, and more. From start to finish, we help bring your vision to life with materials tailored to your course and students' needs.
Instructor Resources
Supporting students starts with supported educators. Save time and simplify your workflow with these powerful tools, analytics, and expert support.
Ready-to-Use Teaching Resources
Save Time with Pre-Built and Customizable Tools: Achieve offers a wealth of ready-made and customizable resources--including assessments, test banks, videos, animations, and classroom activities--all designed to save you time and enhance your teaching. Explore the instructor resources available for your course through a free Achieve sample course!
Powerful Classroom Analytics
Stay on top of your class's progress with powerful analytics tools. Achieve’s gradebook and reporting features track student performance, giving educators the insights they need to provide support at the right time. With iClicker, get instant feedback on student understanding and adjust lessons in real-time to ensure no one falls behind.
Dedicated Instructor Support, Always
Macmillan Learning’s team is here to help with tailored resources, training, demos, and best practices to meet your teaching goals. Need support? Schedule a demo or training anytime.
The Impact of Learning Science and Research
Empower student success with evidence-based product experiences in biochemistry.
See the ResearchLMS Integration
Sync Macmillan Learning tools with your LMS for easy access to assignments, grades, and course materials—all in one place.
Learn About LMS IntegrationInclusive Access
Provide all students with affordable, day-one access to digital course materials through your LMS.
Learn About Inclusive AccessUpcoming Events and Opportunities
Stay connected with the latest events and opportunities designed to help you learn, connect, and support your teaching.
Resource
Are you ready for Title II?
Title II changes are coming soon and Macmillan Learning is here to help you prepare. Learn what Title II means for you and how Macmillan Learning can help you confidently navigate this important shift.
Resource
A Deeper Dive into Title II
Title II is more than a policy, it’s a commitment to equity. It sets clear standards and reinforces that access for everyone belongs at the heart of education. Explore our Title II checklist, expert blog posts, and FAQs to better understand what’s changing and how to prepare.
Webinar
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Today’s biggest topics—AI, accessibility, workforce readiness, the economy—are too important to be reduced to empty catchphrases. Join top voices in education, policy, and economics for conversations packed with actionable insights and strategies to turn ideas into impact.
Explore the Latest in Biochemistry
Stay updated on trending topics, news, and valuable resources to keep you ahead in the world of biochemistry.
Blog
Empowering Student Self-study in Biochemistry
In this Coffee with Colleagues session, Dr. Blythe Janowiak and Dr. Charlotte de Araujo shared practical strategies using study guides, Achieve homework, the AI Tutor, and iClicker to support student learning and engagement.
Blog
Biochemistry Resources Built for TODAY’s Students
Textbooks alone don’t cut it anymore. Students need dynamic, intuitive, and engaging tools that make biochemistry click. Enter Lehninger Biochemistry: Core Concepts and Applications—the newest biochemistry resource designed for today’s students.
Blog
What’s New in Biochemistry: A Short Course 5e?
From the Biochemical Timescale to deeper problem-solving tools and researcher spotlights, this edition makes biochemistry more relevant, accessible, and exciting than ever before. Explore all the updates below!
