Cover: Scientific American Biology for a Changing World with Physiology,, 5th Edition by Michele Shuster; Janet Vigna; Matthew Tontonoz

Scientific American Biology for a Changing World with Physiology,

Fifth Edition  ©2026 Michele Shuster; Janet Vigna; Matthew Tontonoz Formats: Achieve, E-book, Print

Authors

  • Headshot of Michele Shuster

    Michele Shuster

    Michèle Shuster, Ph.D., is the Associate Dean for Research in the College of Arts and Sciences at New Mexico State University in Las Cruces, New Mexico. In her life as a Professor in the Biology Department, she focused on biology teaching and learning and taught introductory biology, microbiology, and cancer biology classes at the undergraduate level. She has also worked on several STEM education grants. Michèle has mentored graduate students and postdoctoral fellows in effective teaching, thereby preparing the next generation of undergraduate educators. She is the recipient of numerous teaching awards, including the Westhafer Award for Teaching Excellence at NMSU. Michèle received her Ph.D. from the Graduate School of Biomedical Sciences at Tufts University School of ­ Medicine, where she studied meiotic ­ chromosome segregation in yeast.


  • Headshot of Janet Vigna

    Janet Vigna

    Janet Vigna, Ph.D., is a Professor of Biology and Associate Dean for Student Success in the College of Liberal Arts and Sciences at Grand Valley State University in Allendale, Michigan. She is a science education specialist, with a passion for training and mentoring K–12 science teachers and teaching nonmajors biology. Her professional interests include the development of curriculum and student success programming that embeds high impact experiential learning. She has been recognized with several teaching awards, including the Michigan Science Teachers Association College Science Teacher of the Year. She received her B.S. in biology from the University of Michigan and her Ph.D. in microbiology from the University of Iowa.


  • Headshot of Matthew Tontonoz

    Matthew Tontonoz

    Matthew Tontonoz is a Ph.D. candidate in the History and Philosophy of Science in the Center for Biology and Society at Arizona State University in Tempe, Arizona, where he is also Editor-in-Chief of the Embryo Project Encyclopedia (embryo.asu.edu). Before returning to graduate school, Matt had been a professional science writer for more than 10 years. Matt received his B.A. in biology from Wesleyan University and his M.A. in the history and sociology of science from the University of Pennsylvania.

Table of Contents

Unit 1: Process of Science

    CHAPTER 1 Process of Science: Do Cell Phones Cause Cancer?

    CHAPTER 2 Chemistry of Life: The Right Stuff With a powerful new telescope, scientists search for signs of life in the universe

    CHAPTER 3 Cell Structure and Function: Wonder Drug

    M1 MILESTONES IN BIOLOGY: Scientific Rebel Lynn Margulis

    CHAPTER 4 Nutrients, Enzymes, Metabolism: Take Your Vitamins

    CHAPTER 5 Energy and Photosynthesis: The Future of Fuel

    CHAPTER 6 Dietary Energy and Cellular Respiration: Taste Sensations

Unit 2: Cell Division and Inheritance

    CHAPTER 7 DNA Structure and Replication: A Matter of Justice

    M2 MILESTONES IN BIOLOGY: The Model Makers Watson and Crick

    CHAPTER 8 Genes to Proteins: Bullet Proof

    CHAPTER 9 Mutations and Genetic Engineering: New Gene, New Me

    CHAPTER 10 Cell Division and Cancer: Fighting Fate

    CHAPTER 11 Simple Inheritance and Meiosis: Catching Breath

    M3 MILESTONES IN BIOLOGY: Mendel’s Garden

    CHAPTER 12 Complex Inheritance: Genetics Q&A

    M4 MILESTONES IN BIOLOGY: Forgotten Forerunner of Epigenetics, Ernest Everett Just

Unit 3: Evolution and Diversity

    CHAPTER 13 Natural Selection and Adaptation: Bugs That Resist Drugs

    CHAPTER 14 Nonadaptive Evolution and Speciation: Urban Evolution

    M5 MILESTONES IN BIOLOGY: Adventures in Evolution Darwin and Alfred Russel Wallace

    CHAPTER 15 Evidence for Evolution: A Fish with Fingers

    CHAPTER 16 Life on Earth: Evolution Q&A

    CHAPTER 17 Prokaryotic Diversity: Invisible You

    CHAPTER 18 Eukaryotic Diversity: Can Rubber Save the Rain Forest?

    M6 MILESTONES IN BIOLOGY: Shaking the Tree

    CHAPTER 19 Human Evolution: Skin Deep

Unit 4: Ecology

    CHAPTER 20 Population Ecology: On the Tracks of Wolves and Moose

    CHAPTER 21 Community Ecology: What’s Happening to Honey Bees

    CHAPTER 22 Ecosystem Ecology: Bringing Bison Back

    M7 MILESTONES IN BIOLOGY: Progress or Poison? Rachel Carson

    CHAPTER 23 Global Climate Change Vital Signs

Unit 5: Plant Biology

    CHAPTER 24 Plant Growth and Reproduction Plants 2.0

    CHAPTER 25 Plant Physiology: Plants Q&A

Unit 6: Animal Physiology

    CHAPTER 26 Overview of Animal Physiology Man vs Mountain

    CHAPTER 27 Digestive System Stomach Troubles

    M8 MILESTONES IN BIOLOGY: Stumbling on a Cure Banting and Best

    CHAPTER 28 Cardiovascular System: Death in Bogalusa

    CHAPTER 29 Respiratory System Peak Performance

    CHAPTER 30 Central Nervous System: Smoke on the Brain

    CHAPTER 31 Reproductive System: Too Many Multiples

    M9 MILESTONES IN BIOLOGY: Pandora’s Dish: Stem Cells

    CHAPTER 32 Immune System: Parallel Pandemics

Product Updates

New and Updated for the Fifth Edition:

  • Visualization and Applications
    • Updated Visuals and Data:
      • New or revised infographics across chapters (e.g., 1.6, 4.1–4.8, 10.10, 18.1, 22.6, 23.3–23.13, 30.1, 32.1).
      • Revised tables and figures covering diverse biology topics from human health to biodiversity.
    • New Writing-to-Learn Activities encourage students to apply knowledge and interpret data through graphs as well as explain their answer in short form writing.
    • Interactive Animation Activities
    • Real World Simulations focus on the most challenging concepts in a non-majors biology course. These scaffolded, interactive lessons help students apply the principles they have learned from the text or lecture in the context of a relevant “real life” question or familiar scenario. Pair well with tutorials as a precursor activity.
    • Virtual Lab Simulations are excellent options for make-up lab assignments; online lab options; or as a pre-lab to help make in-lab more efficient and effective.
  • Personalized Study and Assessment
    • AI Student Tutor uses a Socratic approach to help students work through homework problems—asking guiding questions rather than providing answers—so they build understanding step by step.
    • Adaptive Quizzing adjusts to each student’s pace, reinforcing understanding through personalized practice.
  • Active Learning Resources and Tools
    • iClicker is included with Achieve for instructors and students.
    • New Active Lecture Slides embed iClicker slides into lecture slide decks to provide easy pause points for student participation during lecture. Available for all 32 chapters and 9 milestones.
    • In-Class Activities. Structured plan to facilitate an activity that encourages student engagement in both face-to-face and remote learning courses. Each guide is based on a single topic and allows students to participate through questions, group work, presentations, and/or simulations.
  • Easy Course Management and Planning
    • Learning Objectives have been updated to match content changes in the text and are tagged on all questions.
    • A new AI-powered short-form writing assistant automatically tags and categorizes student responses—helping you grade by theme, identify trends, and save time without losing the personal touch.
    • Over 3600 New Test Bank questions into the Achieve Question Library.
  • New and Updated Book Content:
    • New Chapter Stories:
      • Ch. 2 – “Are We Alone?” featuring the James Webb Space Telescope and the search for extraterrestrial life.
      • Ch. 4 – “Supplementing Science” on the evolving science behind dietary supplements.
      • Ch. 6 – “The Art and Science of Fermented Foods.”
      • Ch. 7 – “A Crime Solved” about Tyrone Day’s wrongful imprisonment overturned by DNA evidence.
      • Ch. 27 – “Digestive Deception” discussing chemical additives and weight loss drugs like Ozempic.
    • New Milestone Chapter: Milestone 4 features Ernest Everett Just and his pioneering work in epigenetics.
    • Expanded COVID-19 Coverage (Ch. 32): Includes comparisons with the 1918 flu, vaccine development and hesitancy, and how mRNA vaccines work.
    • Writing has been updated to be more representative and promote a sense of belonging.

Fuel engagement and deepen learning with real, relevant biology.

Biology for a Changing World brings science to life through powerful, real-world stories that make biology relevant, engaging, and unforgettable. Each chapter begins with a compelling narrative—whether it’s the James Webb Space Telescope and the search for extraterrestrial life, how DNA evidence overturned a wrongful conviction, or the science of weight-loss drugs like Ozempic. These stories hook students with context that matters to their lives. Magazine-style visuals, clear infographics, and story-driven learning ensure that students not only understand biology but also see why it matters.

In this new edition, fresh stories and hands-on learning tools deepen engagement. Pre-lecture videos prepare students for class, the new AI study Coach provides personalized practice, and virtual labs and real-world simulations let students experience how science is done. For many, this may be their only science course—so it’s designed to leave them with lasting scientific literacy, critical thinking skills, and the confidence to apply biology in their personal choices and as citizens of a changing world.

Success Stories

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See how the resources in Achieve help you engage students before, during, and after class.

Prof. Jennifer Duncan

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Here’s why educators who use Achieve would recommend it to their peers.

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Michele Shuster; Janet Vigna; Matthew Tontonoz | Fifth Edition | ©2026 | ISBN:9781319526153

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